Cancer Immunology
New findings reported from Kobe University, Department of Pathology describe advances in cancer immunology
Published in Blood Weekly, November 5th, 2009
Current study results from the report, 'Direct cancer-stromal interaction increases fibroblast proliferation and enhances invasive properties of scirrhous-type gastric carcinoma cells,' have been published. "Scirrhous-type gastric carcinoma (SGC) exhibits an extensive submucosal fibrosis and extremely poor patient prognosis. We investigated the importance of the cancer-stromal interaction in the histogenesis of SGC," researchers in Kobe, Japan report.
"Gastric fibroblasts NF-25 and intestinal fibroblasts NF-j2 were co-cultured with SGC-derived (HSC-39) or non-SGC-derived (HSC-57 and HSC-64) cells. To identify genes that are up-or downregulated in NF-25, complementary...
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Source: Blood Weekly (2009-11-05)
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