Published in Blood Weekly, December 10th, 2009
"Specifically, randomized phase III designs focus on improvements that are more significant statistically than medically and put an emphasis on avoiding a false positive result that is more appropriate for diseases that are curable, in contrast to acute leukemias The resultant large sample sizes needed for each treatment restrict the trial to one or two new treatments.. although historical reality Suggests the difficulty in knowing, without...
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Source: Blood Weekly (2009-12-10)
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