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Leukemia Prognosis

Research from University of Regensburg, Institute of Pathology provides new data on leukemia prognosis

Published in Blood Weekly, December 10th, 2009

Current study results from the report, 'Different proliferative and survival capacity of CLL-cells in a newly established in vitro model for pseudofollicles,' have been published. "Chronic lymphocytic leukemia (CLL) is a malignancy of mature B-lymphocytes that manifests in a variety of clinical courses. The accumulation of CLL-cells is primarily caused by defective apoptosis; however, a higher proliferative capacity has also been found to correlate with poorer prognostic factors," scientists writing in the journal Leukemia report.

"Proliferating CLL-cells are confined to specialized structures called pseudofollicles, which contain CLL-cells, T-lymphocytes, and...

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