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Bone Research

Scientists at University of Michigan release new data on bone research

Published in Blood Weekly, December 10th, 2009

"The incidence of ligament injury has recently been estimated at 400,000/year. The preferred treatment is reconstruction using an allograft, but outcomes are limited by donor availability, biomechanical incompatibility, and immune rejection," scientists writing in the Journal of Biomechanical Engineering - Transactions of the ASME report.

"The creation of an engineered ligament in vitro solely from patient bone marrow stromal cells (has the potential to greatly enhance outcomes in knee reconstructions. Our laboratory has developed a scaffoldless method to engineer three-dimensional (3D) ligament and bone constructs from rat bone marrow stem cells in vitro....

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