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Graft Versus Host Disease Therapy

Studies from University of Utah add new findings in the area of graft versus host disease therapy

Published in Blood Weekly, December 17th, 2009

Researchers detail in 'A phase I/II study of the safety and efficacy of the addition of sirolimus to tacrolimus/methotrexate graft versus host disease prophylaxis after allogeneic haematopoietic cell transplantation in paediatric acute lymphoblastic leukaemia (ALL),' new data in graft versus host disease. According to recent research from the United States, "Sirolimus has been shown to have activity against human acute lymphoblastic leukaemia at serum levels used for immunosuppression. We hypothesized that the addition of sirolimus to a tacrolimus/methotrexate graft-versus-host disease (GVHD) prophylaxis regimen would decrease relapse after haematopoietic stem cell transplantation and...

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