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Myeloma Genetics

New myeloma genetics study findings have been published by scientists at Mayo Clinic, Department of Hematology-Oncology

Published in Blood Weekly, January 7th, 2010

Fresh data on myeloma are presented in the report 'International Myeloma Working Group molecular classification of multiple myeloma: spotlight review.' According to recent research from the United States, "Myeloma is a malignant proliferation of monoclonal plasma cells. Although morphologically similar, several subtypes of the disease have been identified at the genetic and molecular level."

"These genetic subtypes are associated with unique clinicopathological features and dissimilar outcome. At the top hierarchical level, myeloma can be divided into hyperdiploid and non-hyperdiploid subtypes. The latter is mainly composed of cases harboring IgH translocations,...

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