Thrombosis
New thrombosis findings from E. Orlowski and co-authors described
Published in Blood Weekly, January 14th, 2010
"This study was designed to determine the role of CD151 in platelet thrombus formation in vivo and define the contribution of platelet vs. endothelial CD151 in regulating platelet thrombus formation in vivo. Using intravital microscopy and ferric chloride (FeCl3) injury of mesenteric arterioles, we found that thrombi formed in CD151+/- and CD151-/- mice were smaller and less stable, than those formed in CD151+/+ mice, with a tendency for embolization," scientists in Melbourne, Australia report.
"Similarly, in Folt's FeCl3-induced carotid injury model, both CD151+/- and CD151-/- mice showed more prolonged times to 95% vessel occlusion than CD151+/+ mice. In addition,...
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Source: Blood Weekly (2010-01-14)
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