Life Sciences

Kurume University, Medical Department reports research in life sciences

Published in Blood Weekly, January 28th, 2010

According to recent research from Fukuoka, Japan, "High mobility group box 1 (HMGB1), a nonhistone chromatin-associated protein, is implicated as a mediator of both infectious and noninfectious inflammatory conditions. Clinical research on this protein in humans just has begun; serum HMGB1 was reported to be elevated in a small number of critically ill patients suffering from sepsis."

"However, the kinetics, distribution and factors associated with circulating HMGB1 are unknown in a general population. In this study, we examined these issues in a large population of healthy subjects. Fasting blood samples were obtained from 626 subjects (237 males and 389 females)....

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Source: Blood Weekly (2010-01-28)

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