Human Papilloma Virus

Data on human papilloma virus reported by H.V.N. Kustersvandevelde and co-researchers

Published in Blood Weekly, January 28th, 2010

According to recent research from Netherlands, "Studies in cervical dysplasia have reported overexpression of the tumour suppressors p14 and p16 - and absence of p53 - in high-risk human papilloma virus (HPV)- associated lesions. In skin carcinogenesis, the relation between these tumour suppressors and HPV remain unclear."

"We evaluated the expression of the tumour suppressors p14, p16 and p53 in pre-malignant and malignant squamous skin tumours, and its relation with risk factors for skin carcinogenesis (HPV, immune status and sun exposure). We performed immunohistochemical stainings for p14, p16 and p53 on paraffin embedded material of 71 pre-malignant squamous skin...

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Source: Blood Weekly (2010-01-28)

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