Ischemia
Research on ischemia published by scientists at Copenhagen University
Published in Blood Weekly, January 28th, 2010
According to a study from Glostrup, Denmark, "This study investigates whether intravitreal administration of glial cell line-derived neurotrophic factor (GDNF) enhances survival of NeuN positive retinal cells in a porcine model of retinal ischemia. 16 pigs were subjected to an ischemic insult where intraocular pressure was maintained at 5 mmHg below mean arterial blood pressure for 2 h. The mean IOP during the ischemic insult was 79.5 mmHg (s.e.m. 2.1 mmHg, n = 15). Three days after the insult the pigs received an intravitreal injection of GDNF microspheres or blank microspheres."
"The pigs were evaluated by way of multifocal electroretinography (mfERG), quantification...
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Source: Blood Weekly (2010-01-28)
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