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Restenosis

Findings from Tohoku University, Medical Department broaden understanding of restenosis

Published in Blood Weekly, January 28th, 2010

According to recent research published in the journal Clinical and Experimental Pharmacology and Physiology, "The aim of the present study was to evaluate the inhibitory effects of the short-term administration of beraprost sodium, a stable prostaglandin I-2 analogue, on neointimal thickening after stenting. To examine the immediate and short-term effects, Z-stents were placed in the iliac veins of 12 dogs, which were randomly assigned to either a beraprost-treated or control (saline) group."

"Beraprost (0.35 mu g/kg per min) or saline (1.5 mL/min) was administered 30 min before stenting and was continued for 5 h thereafter. Platelet aggregation was measured...

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