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Arteriosclerosis Immunology

Research in the area of arteriosclerosis immunology reported from University of Tokushima, Institute of Health Bioscience

Published in Blood Weekly, February 4th, 2010

New research, 'Role of hypoxia-inducible factor 1alpha in T cells as a negative regulator in development of vascular remodeling,' is the subject of a report. "Recent studies have shown that the cellular immune response in the development of vascular remodeling modulates the resulting pathological alterations. We show that hypoxia-inducible factor 1 (Hif-1) (specifically expressed in T cells) is involved in the immune response to vascular remodeling that accompanies arteriosclerosis," researchers in Tokushima, Japan report.

"To study the role of T cells in the development of vascular remodeling, femoral arterial injury induced by an external vascular polyethylene cuff...

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