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Familial Combined Hyperlipidemia Genetics

Reports from University of California, Department of Human Genetics advance knowledge in familial combined hyperlipidemia genetics

Published in Blood Weekly, February 4th, 2010

Fresh data on familial combined hyperlipidemia are presented in the report 'Identification of two common variants contributing to serum apolipoprotein B levels in mexicans.' "Although the Mexican population has a high predisposition to dyslipidemias and premature coronary artery disease, this population is underinvestigated for the genetic factors conferring the high susceptibility. This study attempted to determine these genetic factors," researchers in the United States report.

"First, we investigated apolipoprotein B (apoB) levels in Mexican extended families with familial combined hyperlipidemia using a two-step testing strategy. In the screening step, we screened...

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