Melanoma
Research data from Julius-Maximilians University, DFG Research Center for Experimental Biomedicine update understanding of melanoma
Published in Blood Weekly, February 4th, 2010
Researchers detail in 'Inhibition of platelet GPIb alpha and promotion of melanoma metastasis,' new data in melanoma. According to a study from Wurzburg, Germany, "Platelet glycoprotein Ibalpha (GPIb alpha) is part of the receptor complex GPIb-V-IX, which has a critical role in hemostasis, especially through interactions with the subendothelial von Willebrand factor. As there is accumulating evidence for a contribution of platelet receptors to hematogenous tumor metastasis, GPIb alpha is an interesting molecule to study in this context."
"We have investigated the effect of GPIb alpha inhibition by monovalent Fab fragments on experimental pulmonary metastasis in a...
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Source: Blood Weekly (2010-02-04)
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