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University of Utah Health Sciences

Groundbreaking research shows platelets can reproduce in circulation

Published in Blood Weekly, February 11th, 2010

University of Utah researchers led an international team of scientists that is the first to report on the previously undescribed ability of platelets to reproduce themselves in the circulation. Their revolutionary findings were published online Jan. 19, 2010, in the journal Blood.

Platelets develop from precursor cells found in the bone marrow, a process that is called thrombopoiesis. During the final stages of thrombopoiesis, platelets are shed from the cytoplasm of their precursors and then enter the bloodstream. Because they lack nuclei, circulating platelets are often referred to as "cytoplasts."

Because DNA resides in the nucleus, platelets were...

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