Stem Cell Research
Investigators at National Defense Medical College, Medical College target stem cell research
Published in Blood Weekly, February 18th, 2010
"Fragmin (low-molecular-weight heparin)/protamine microparticles (F/P MPs) immobilize to culture plates, thereby retaining the binding of heparin-binding cytokines such as human stem cell factor (SCF). The purpose of this study was to evaluate the ability of F/P MP-coating to immobilize, stabilize, and enhance SCF-activity," scientists writing in the Journal of Biomedical Materials Research Part B - Applied Biomaterials report.
"Cell assays showed that SCF and preimmobilized SCIF on F/P MP-coated plates significantly stimulated the proliferation of human erythroleukemia cell line TF-1 in a concentration A e pendent manner. Heparin and fragmin enhanced SCF-induced...
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Source: Blood Weekly (2010-02-18)
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