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Atherosclerosis

New findings reported from Toho University, Medical Department describe advances in atherosclerosis

Published in Blood Weekly, February 25th, 2010

According to recent research from Tokyo, Japan, "Scavenger receptors type I and H (SRBI/II) have dual roles in both atherogenic and antiatherogenic functions through interactions with lipoproteins and their expression in macrophages; however, the distribution and density of SRBI/II-positive macrophages and smooth muscle cells (SMCs) as well as their association with lipid metabolism-related proteins in atherosclerotic intima of the human aorta remain unclear. Autopsied aortic tissues were double-immunostained with SRBI/BII and smooth muscle actin or macrophage-specific antibodies."

"The density of SRBI/BII-positive SMCs and macrophages in intimal lesion was measured....

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