Enzyme Research

Researchers from Academy of Science publish new studies and findings in the area of enzyme research

Published in Blood Weekly, March 4th, 2010

"The goal Of Our Study was to determine a contribution of nNOS to the increase of brain NO synthase activity induced by chronic N-acetylcysteine (NAC) treatment. Young 4-week-old male Wistar Kyoto rats (WKY) and spontaneously hypertensive rats (SHR) were subjected to treatment with NAC (1.5 g/kg/day) for 8 weeks," scientists writing in the Journal of Physiology and Pharmacology report.

"At the end of experiment total NOS activity was determined in the brainstem and cerebellum with and without specific nNOS inhibitor S-methyl-L-thiocitrulline (SMTC, 10(-6) mol/l) by measuring the formation of citrulline from L-[H-3] arginine. Chronic NAC treatment had no effect on...

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Source: Blood Weekly (2010-03-04)

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