Myeloid Leukemia
Researchers from University of Hong Kong, Department of Medicine publish new studies and findings in the area of myeloid leukemia
Published in Blood Weekly, March 11th, 2010
Research findings, 'FLT3/internal tandem duplication subclones in acute myeloid leukemia differ in their engraftment potential in NOD/SCID mice,' are discussed in a new report. According to a study from Hong Kong, "In this study, we tested if FLT3/internal tandem duplication (ITD) in acute myeloid leukemia (AML) might occur at different hierarchical stages during leukemogenesis. In 56 AML cases, 10 showed FLT3/ITD (single ITD=5; multiple ITD=5)."
"Myeloblasts from seven cases (CD34-selected=4; unselected=3) were transplanted into NOD/SCID mice. Five cases engrafted successfully into 14 mice. Two patients carried single FLT3/ITD subclones, which were maintained during...
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Source: Blood Weekly (2010-03-11)
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