Leptospirosis

Research from F. Vernelpauillac and co-researchers yields new findings on leptospirosis

Published in Blood Weekly, March 18th, 2010

According to recent research from Noumea, New Caledonia, "Parameters predicting the evolution of leptospirosis would be useful for clinicians, as well as to better understand severe leptospirosis, but are scarce and rarely validated. Because severe leptospirosis includes septic shock, similarities with predictors evidenced for sepsis and septic shock were studied in a hamster model."

"Using an LD50 model of leptospirosis in hamsters, we first determined that 3 days post-infection was a time-point that allowed studying the regulation of immune gene expression and represented the onset of the clinical signs of the disease. In the absence of tools to assess serum...

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Source: Blood Weekly (2010-03-18)

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