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Antiphospholipid Syndrome Risk Factors

Studies from University of Milan, Department of Internal Medicine add new findings in the area of antiphospholipid syndrome risk factors

Published in Blood Weekly, March 18th, 2010

Current study results from the report, 'Patients with antiphospholipid syndrome display endothelial perturbation,' have been published. According to a study from Italy, "There is strong evidence that antiphospholipid antibodies (aPL) perturb endothelium both in vitro and in experimental animal models. by inducing a vasculopathy and an endothelial pro-inflammatory/coagulant phenotype. However, few contrasting studies raised the issue about the possibility to detect a comparable endothelial perturbation in anti-phospholipid syndrome (APS) patients."

"The aim of this observational case-control study was to evaluate several parameters of endothelial perturbation in patients...

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