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University of Pittsburgh Schools of the Health Sciences

Kidney injury linked to greater risk of death among pneumonia patients

Published in Blood Weekly, March 18th, 2010

Patients hospitalized with even mild to moderate community-acquired pneumonia who develop acute kidney injury (AKI) are more likely to die after discharge than pneumonia patients whose kidneys remain healthy, according to a University of Pittsburgh School of Medicine study in the February issue of Kidney International. The study also found a strong relationship between AKI and levels of inflammatory biomarkers.

Doctors have long known that sepsis, a systemic response to severe infection, can trigger abnormalities in kidney function that contribute to higher mortality rates, but the impact of AKI in people with milder infections has not been well characterized, said lead...

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