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T-Cell Lymphoma Immunology

Study findings from Chi-Mei Medical Center, Department of Pathology broaden understanding of t-cell lymphoma immunology

Published in Blood Weekly, April 1st, 2010

New investigation results, 'Angioimmunoblastic T-cell lymphoma of cytotoxic T-cell phenotype containing a large B-cell proliferation with an undersized B-cell clonal product,' are detailed in a study published in Applied Immunohistochemistry & Molecular Morphology. "Angioimmunoblastic T-cell lymphoma is a nodal peripheral T-cell lymphoma considered to be derived from CD4 follicular helper T cells. It is characterized by the proliferation of arborizing vessels, hyperplastic follicular dendritic cells, and a polymorphous lymphoid infiltrate including large B immunoblasts, which could be polyclonal, oligoclonal, or monoclonal," researchers in Tainan, Taiwan report.

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