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Antimicrobials

New antimicrobials findings from E.L. Perry and co-authors described

Published in Blood Weekly, April 1st, 2010

"Infection remains the main challenge to percutaneous, intramedullary osseointegrated implant technology. The purpose of this investigation was to determine if a broad spectrum antimicrobial, Ceragenin ™ (CSA-13) could prevent pin track infections in a percutaneous tibial pin site in a sheep model," scientists writing in the Journal of Biomedical Materials Research Part B - Applied Biomaterials report.

"In 20 sheep, a smooth titanium alloy pin/implant was inserted percutaneously through the medial skin and both cortices of the proximal tibia. In 10 sheep, the pin/skin interface was treated with a CSA-13-embedded foam pad. Ten sheep served as controls...

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