University of Utah Health Sciences

Targeting blood vessels, immune system may offer way to stop infection-caused inflammation

Published in Blood Weekly, April 1st, 2010

Treating virulent influenza, sepsis, and other potentially deadly infections long has focused on looking for ways to kill viruses and bacteria. But new research from the University of Utah and Utah State University shows that modulating the body's own overeager inflammatory response to infection may help save more lives.

In a study published March 17 in Science Translational Medicine, researchers led by U of U cardiologist Dean Y. Li, M.D., Ph.D., professor of internal medicine and director of the Molecular Medicine Program, shows that protecting blood vessels from hyper-inflammatory response to infection reduced mortality rates in mouse models of avian flu and sepsis...

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Source: Blood Weekly (2010-04-01)

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