Alpha-thalassemia
New alpha-thalassemia study findings recently were published by M. Neishabury and co-researchers
Published in Blood Weekly, April 1st, 2010
"From 362 thalassemia cases referred to adult thalassemia clinic of the Iranian blood transfusion organization (IBTO) for genotyping, 103 cases (28.5%) had a common primary disease factor, IVSII-1 mutation in homozygous state. 61 (59.2%) of these individuals represented thalassemia major and 42 (40.8%) thalassemia intermedia clinical phenotype. To re-evaluate our current diagnostic criteria, XmnI (G)gamma polymorphism and coexistence of alpha thalassemia mutations, frequently recalled as important factors modifying the clinical phenotype of homozygous beta zero thalassemia cases in our country, were examined in both groups," investigators in Iran report.
"No...
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Source: Blood Weekly (2010-04-01)
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