Monoclonal Antibodies
Researchers from Amgen, Inc. report details of new studies and findings in the area of monoclonal antibodies
Published in Blood Weekly, April 1st, 2010
Fresh data on monoclonal antibodies are presented in the report 'Identification of a sensitive anti-erythropoietin receptor monoclonal antibody allows detection of low levels of EpoR in cells.' According to a study from the United States, "Erythropoietin (Epo) binds and activates the Epo receptor (EpoR) on the surface of erythroid progenitor cells resulting in formation of erythrocytes. Recently, EpoR was reported to be expressed on non-erythroid cells suggesting a role for Epo outside of erythropoiesis."
"However those studies employed antibodies with questionable specificity and the significance of the observations are controversial. In order to accurately determine...
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Source: Blood Weekly (2010-04-01)
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