Lymphoma Immunology

INSERM reports research in lymphoma immunology

Published in Blood Weekly, May 6th, 2010

Current study results from the report, 'mu-Opioid receptor is induced by IL-13 within lymph nodes from patients with Sezary syndrome,' have been published. "Endogenous opioid peptides mainly produced by neurons are also released by immune cells. They bind to mu-(mu-opioid receptor, MOR), delta-, and kappa-opioid receptors," scientists in Toulouse, France report.

"On the basis of studies on mice showing that MOR is the main mediator of the deleterious effects of opioids on immunity, we wondered whether MOR, absent under normal conditions, is expressed in some pathological situations such as lymphomas. mRNA expression for all three opioid receptors was examined in lymph...

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Source: Blood Weekly (2010-05-06)

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