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Scientists at Shanghai Institute of Materia Medica target pharmaceuticals

Published in Blood Weekly, May 6th, 2010

A report, 'Quantification of the major metabolites of bromhexine in human plasma using RRLC-MS/MS and its application to pharmacokinetics,' is newly published data in Journal of Pharmaceutical and Biomedical Analysis. "(E)-4-hydroxydemethylbromhexine (E-4-HDMB) and (E)-3-hydroxydemethylbromhexine (E-3-HDMB) were found as major metabolites, while (Z)-4-hydroxydemethylbromhexine and (Z)-3-hydroxydemethylbromhexine as minor metabolites of bromhexine in human plasma. These compounds were identified in comparison with synthetic authentic samples," scientists in Shanghai, People's Republic of China report.

"A sensitive and selective rapid resolution liquid...

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