Thrombosis
Researchers at Emory University, Department of Anesthesiology target thrombosis
Published in Blood Weekly, May 13th, 2010
Fresh data on thrombosis are presented in the report 'Anti-factor IXa Aptamer reduces propagation of thrombin generation in plasma anticoagulated with warfarin.' According to recent research published in the journal Thrombosis Research, "Warfarin is routinely used in the prevention and treatment of prothrombotic events. During initiation of warfarin therapy levels of factor (F) VII and protein C decrease rapidly but prothrombin, FIX and FX decline much slower."
"Therefore, propagation of thrombin generation (TG) remains unaffected much longer, increasing the risk of inadequate anticoagulation. Recently, a novel agent, anti-IXa aptamer, RB006, has been developed....
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Source: Blood Weekly (2010-05-13)
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