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Stem Cell Research

Studies from Taichung Veterans General Hospital describe new findings in stem cell research

Published in Blood Weekly, May 13th, 2010

"Human amniotic fluid derived mesenchymal stem cells (AFMSCs) have been shown to promote peripheral nerve regeneration, and the local delivery of neurotrophic factors may additionally enhance nerve regeneration capacity. The present study evaluates whether the transplantation of glia cell line derived neurotrophic factor (GDNF) modified human AFMSCs may enhance regeneration of sciatic nerve after a crush injury," scientists in Taichung, Taiwan report.

"Peripheral nerve injury was produced in Sprague-Dawley rats by crushing the left sciatic nerve using a vessel clamp. Either GDNF-modified human AFMSCs or human AFMSCs were embedded in Matrigel and delivered to the injured...

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