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Cardiology

Data from Texas A&M University, Health Science Center provide new insights into cardiology

Published in Blood Weekly, May 13th, 2010

New research, 'Caspase-3 knock-down reverses contractile dysfunction induced by sepsis in adult rat ventricular myocytes,' is the subject of a report. "The present study tested the hypothesis that selective caspase-3 (C-3) knock-out would regulate the contractile actions of noradrenaline (NA) in the dysfunction of adult rat ventricular myocytes (ARVMs) induced by sepsis. Here, we have studied the contractile response of ARVMs, transfected with C-3 small interfering RNA (C-3 siRNA), to NA," scientists writing in the British Journal of Pharmacology report.

"EXPERIMENTAL APPROACH: Single ARVMs were isolated from the hearts of male Sprague-Dawley rats 3 days after...

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