Myelodysplastic Syndrome
New findings in myelodysplastic syndrome described from Seoul National University, Department of Laboratory Medicine
Published in Blood Weekly, May 13th, 2010
New investigation results, 'p15INK4b methylation correlates with thrombocytopenia, blast percentage, and survival in myelodysplastic syndromes in a dose dependent manner: quantitation using pyrosequencing study,' are detailed in a study published in Leukemia Research. "We investigated how the quantity of p15INK4b methylation related to International Prognosic Scoring System variables and survival in 74 patients with de novo myelodysplastic syndrome (MDS). Pyrosequencing of 11 consecutive CpG sites of the p15INK4b promotor region was performed, with the extent of CpG cytosine methylation assessed in terms of methylation level (MtL)," scientists writing in the journal Leukemia...
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Source: Blood Weekly (2010-05-13)
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