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Blood Coagulation Factors

Reports by Y. Shachaf and co-researchers describe recent advances in blood coagulation factors

Published in Blood Weekly, May 20th, 2010

"Our research is focused on the design of hydrogel biomaterials that can be used for 3-D cell encapsulation and tissue engineering. In this study, our goal was to engineer a temperature-responsive biomaterial to possess bioactive properties using polymer and protein chemistry, and at the same time provide the biomaterial with susceptibility to cell-mediated remodeling," scientists in Haifa, Israel report.

"Toward this goal, we developed a biomimetic material that can harness the bioactive properties of fibrinogen and the unique structural properties of Pluronic ® F127. Pluronic ® F127 is a synthetic block copolymer that exhibits reverse thermal gelation (RTG)...

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