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Blood Research

Research in the area of blood research reported from University of Erlangen-Nuremberg, Institute of Experimental and Clinical Pharmacology and Toxicology

Published in Blood Weekly, May 20th, 2010

New investigation results, 'Absorption and distribution of etoricoxib in plasma, CSF, and wound tissue in patients following hip surgery--a pilot study,' are detailed in a study published in Naunyn-schmiedeberg's Archives of Pharmacology. "The perioperative administration of selective cyclooxygenase-2 (COX-2)-inhibitors to avoid postoperative pain is an attractive option: they show favorable gastro-intestinal tolerability, lack inhibition of blood coagulation, and carry a low risk of asthmatic attacks. The purpose of this study was to determine the cerebrospinal fluid (CSF), plasma, and tissue pharmacokinetics of orally administered etoricoxib and to compare it with effect data,...

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