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Myocardial Ischemia

Research results from Y. Wang and co-authors update knowledge of myocardial ischemia

Published in Blood Weekly, May 20th, 2010

According to recent research from People's Republic of China, "Female sex hormones may have protective effects against arrhythmias, including reperfusion arrhythmias (RAs), but the mechanisms are still not completely known. Serial changes in rat hearts (rhythm, apoptosis and the its infuencing factors; cardiac vinculin mRNA expression and connexin43 (Cx43) dephosphorylation) were examined during periods of ischemia reperfusion with and without estrogen treatment."

"After reperfusion, although the incidence of arrhythmias became higher in both the vehicle-group and estrogen-group, compared with the ischemia period, estrogen prevented reperfusion-induced upregulation of...

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