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Thrombocytopenia

Data on thrombocytopenia detailed by F. Zaja and co-authors

Published in Blood Weekly, May 20th, 2010

Scientists discuss in 'Dexamethasone plus rituximab yields higher sustained response rates than dexamethasone monotherapy in adults with primary immune thrombocytopenia' new findings in thrombocytopenia. "Previous observational studies suggest that rituximab may be useful in the treatment of primary immune thrombocytopenia (ITP). This randomized trial investigated rituximab efficacy in previously untreated adult ITP patients with a platelet count of 20 x 10(9)/L or less," investigators in Udine, Italy report.

"One hundred three patients were randomly assigned to receive 40 mg/d dexamethasone for 4 days with or without 375 mg/m2 rituximab weekly for 4 weeks....

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