Drug Development

New research on drug development from INSERM summarized

Published in Blood Weekly, May 20th, 2010

"Ribavirin pharmacokinetic and exposure effect trials based on either plasma or serum concentrations have yielded diverging results. This study aimed to compare ribavirin concentrations in serum and plasma and to investigate the influence of blood collection and preanalytical conditions on ribavirin concentration stability," scientists writing in the journal Therapeutic Drug Monitoring report.

"Blood samples from patients with hepatitis virus C and receiving ribavirin were collected in plain (dry) tubes, in tubes containing ethylenediaminetetra-acetic acid or lithium-heparinate, in Type II Serum Separating Tubes with clot activator, or Type II lithium heparinate...

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Source: Blood Weekly (2010-05-20)

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