Plasminogen Activators
Researchers' work from University Hospital, Department of Neurology focuses on plasminogen activators
Published in Blood Weekly, May 20th, 2010
Scientists discuss in 'Combination of tissue-plasminogen activator with erythropoietin induces blood-brain barrier permeability, extracellular matrix disaggregation, and DNA fragmentation after focal cerebral ischemia in mice' new findings in plasminogen activators. According to a study from Essen, Germany, "After 1 clinical study in which recombinant erythropoietin (EPO) protected against ischemic stroke and improved clinical outcome, the German multicenter EPO trial recently reported increased mortality in stroke patients receiving EPO after tissue-plasminogen activator (t-PA)-induced thrombolysis. The reasons for the adverse effects of EPO in t-PA-treated patients are unknown."
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Source: Blood Weekly (2010-05-20)
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