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Transfusion Medicine

Studies from University of Hong Kong, Department of Anaesthesiology provide new data on transfusion medicine

Published in Blood Weekly, May 20th, 2010

Researchers detail in 'Remifentanil post-conditioning attenuates cardiac ischemia-reperfusion injury via kappa or delta opioid receptor activation,' new data in transfusion medicine. According to recent research from Hong Kong, "Ischemic pre-or post-conditioning of the heart has been shown to involve opioid receptors. Remifentanil, an ultra-short-acting selective mc opioid receptor agonist in clinical use, pre-conditions the rat heart against ischemia-reperfusion injury."

"This study investigates whether remifentanil post-conditioning is also cardioprotective. Remifentanil post-conditioning (5-min infusion at 1, 5, 10 or 20 microg/kg/min) or ischemic post-conditioning...

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