Tissue Engineering

Research from Singapore National University reveals new findings on tissue engineering

Published in Blood Weekly, June 3rd, 2010

According to a study from Singapore, Singapore, "Organ restoration via cell therapy and tissue transplantation is limited by impaired graft survival. We tested the hypothesis that ascorbic acid ( AA) reduces cell death in myocardial grafts both in vitro and in vivo and introduced a new model of autologous graft vascularization for later transplantation."

"Luciferase (Fluc)- and green fluorescent protein (GFP)-expressing H9C2 cardiomyoblasts were seeded in gelatin scaffolds to form myocardial artificial grafts (MAGs). MAGs were supplemented with AA ( 5 or 50 mu mol/L) or plain growth medium. Bioluminescence imaging showed increased cell photon emission from day 1 to 5 in...

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Source: Blood Weekly (2010-06-03)

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