Hematologic Agents
Research on hematologic agents published by M. Ben Mansour et al
Published in Blood Weekly, June 10th, 2010
Research findings, 'Highly sulfated dermatan sulfate from the skin of the ray Raja montagui: anticoagulant activity and mechanism of action,' are discussed in a new report. According to recent research from Monastir, Tunisia, "The dermatan sulfate (DS) isolated from the ray skin Raja montagui was identified and characterized. Its average molecular weight (Mw) and sulfate content were 39 kDa and 25% w/w, respectively."
"This DS prolonged thrombin time and activated partial thromboplastin time and inhibited the thrombin generation in a concentration-dependent manner whereas it had no effect on the anti-Xa assay and on platelet function. Data from the anti-IIa assay...
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Source: Blood Weekly (2010-06-10)
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