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Multiple Myeloma

Study data from University Hospital, Department of Internal Medicine update knowledge of multiple myeloma

Published in Blood Weekly, June 10th, 2010

A new study, 'Treatment response to bortezomib in multiple myeloma correlates with plasma hepatocyte growth factor concentration and bone marrow thrombospondin concentration,' is now available. "Multiple myeloma (MM) is associated with increased rate of bone marrow angiogenesis. Increased concentration of hepatocyte growth factor (HGF) is associated with poor prognosis in patients treated with conventional chemotherapy or thalidomide," scientists in Brno, Czech Republic report.

"We have shown previously that decreased level of thrombospondin, an angiogenesis inhibitor, correlates with poor response to high-dose chemotherapy. The aim of our current study was to evaluate...

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