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Cholinesterases

Researchers from University Federal of Sao Paulo, Department of Pharmacology discuss findings in cholinesterases

Published in Blood Weekly, June 17th, 2010

Researchers detail in 'Gender-related differences in circadian rhythm of rat plasma acetyl- and butyrylcholinesterase: effects of sex hormone withdrawal,' new data in cholinesterases. "The role of acetylcholinesterase (AChE) in the termination of the cholinergic response through acetylcholine (ACh) hydrolysis and the involvement of plasma butyrylcholinesterase (BuChE), mainly of hepatic origin, in the metabolism of xenobiotics with ester bonds is well known. Besides, BuChE has a crucial role in ACh hydrolysis, especially when selective anticholinesterases inhibit AChE," investigators in Sao Paulo, Brazil report.

"Herein, we analyzed the gender-related differences and...

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