Hematology
Recent findings in hematology described by researchers from University of Verona, Department of Medicine
Published in Blood Weekly, July 22nd, 2010
Investigators publish new data in the report 'ZAP-70 expression is associated with increased risk of autoimmune cytopenias in CLL patients.' "Autoimmune cytopenias (AIC) are frequent in chronic lymphocytic leukemia (CLL) patients, but risk factors and prognostic relevance of these events are controversial. Data about the influence on AIC of biological prognostic markers, as ZAP-70, are scanty," investigators in Italy report.
"We retrospectively evaluated AIC in 290 CLL patients tested for ZAP-70 expression by immunohistochemistry on bone marrow biopsy at presentation. They were 185 men, median age 63 years, 77.9% Binet stage A, 17.6% B and 4.5% C. AIC occurred in 46...
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Source: Blood Weekly (2010-07-22)
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