Nuclear Medicine
Researchers at Yale University publish new data on nuclear medicine
Published in Blood Weekly, September 2nd, 2010
Research findings, 'Quantification of smoking-induced occupancy of beta2-nicotinic acetylcholine receptors: estimation of nondisplaceable binding,' are discussed in a new report. According to a study from the United States, "5-(123)I-iodo-85380 ((123)I-5-IA) is used to quantitate high-affinity nicotinic acetylcholine receptors (beta(2)-nAChRs) on human SPECT scans. The primary outcome measure is V(T)/f(P), the ratio at equilibrium between total tissue concentration (free, nonspecifically bound, and specifically bound) and the free plasma concentration."
"Nondisplaceable uptake (free plus nonspecific) of (123)I-5-IA has not been measured in human subjects. Nicotine has...
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Source: Blood Weekly (2010-09-02)
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