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Blood Research

Research on blood research published by scientists at University of Wurzburg, Research Center

Published in Blood Weekly, October 7th, 2010

Research findings, 'ADF/n-cofilin-dependent actin turnover determines platelet formation and sizing,' are discussed in a new report. According to recent research published in the journal Blood, "The cellular and molecular mechanisms orchestrating the complex process by which bone marrow megakaryocytes form and release platelets remain poorly understood. Mature megakaryocytes generate long cytoplasmic extensions, proplatelets, which have the capacity to generate platelets."

"Although microtubules are the main structural component of proplatelets and microtubule sliding is known to drive proplatelet elongation, the role of actin dynamics in the process of platelet...

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