Portal Hypertension

Data on portal hypertension published by Y. Horai and colleagues

Published in Blood Weekly, November 4th, 2010

"We report a 29-year-old woman with a 2.5 year history of mixed connective tissue disease (MCTD) who developed idiopathic portal hypertension (IPH) and thrombocytopenia as a result of hypersplenism. She had recurrent esophagogastric variceal rupture," researchers in Fukuoka, Japan report.

"Hematological examination also revealed low levels of protein C activity. The liver biopsy specimen showed non-specific mild inflammation and no thrombi. However, portal vein thrombosis developed after splenectomy," wrote Y. Horai and colleagues.

The researchers concluded: "This was a rare case of severe complications of IPH accompanying MCTD and protein C...

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Source: Blood Weekly (2010-11-04)

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