Leukemia
Investigators at University of Texas, M. D. Anderson Cancer Center Zero in on Leukemia
Published in Blood Weekly, January 20th, 2011
2011 JAN 20 -- Research findings, 'FLT3 and NPM1 mutations in myelodysplastic syndromes: Frequency and potential value for predicting progression to acute myeloid leukemia,' are discussed in a new report. "We reviewed FLT3 and NPM1 mutation data in a large cohort of patients with myelodysplastic syndrome (MDS). The frequencies of FLT3 and NPM1 mutation were 2.0% and 4.4%, respectively, and mutations were restricted to cases of intermediate-and high-risk MDS," scientists writing in the American Journal of Clinical Pathology report.
"Cytogenetic abnormalities were identified in 46.9% of cases. FLT3 mutations were associated with a complex karyotype...
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Source: Blood Weekly (2011-01-20)
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