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Organ Transplantation

Reports Outline Organ Transplantation Research from F. Casiraghi and Colleagues

Published in Blood Weekly, January 27th, 2011

2011 JAN 27 -- "of review Multipotent mesenchymal stromal cells (MSCs) possess powerful immunomodulatory activity highlighting the potential for their clinical translation in solid organ transplantation. In this review, we summarize recent advances in understanding MSC immunomodulatory effect in vitro and in experimental transplant models and discuss topics of crucial importance for the future clinical use of MSCs as immunotherapy in solid organ transplantation," scientists writing in the journal Current Opinion in Organ Transplantation report.

"Recent findings MSCs strongly inhibited T-cell activity in vitro and exerted similar inhibitory effects on...

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